Survival-associated eQTLs across different cancer types
We identified 22,212 eQTLs associated with patient overall survival across different cancer types at FDR < 0.05.
|
Cancer type
|
SNP ID
|
SNP position (hg19)
|
Alleles (A/a)
|
log-rank test p-value
|
Sample size
|
Median survival time AA
|
Median survival time Aa
|
Median survival time aa
|
|
|---|---|---|---|---|---|---|---|---|---|
| GBM | rs57529153 | chr17:27011560 | T/A | 2.22E-5 | 146 | 12 | 8.37 | 1.2 | KM Plot |
| GBM | rs57577420 | chr17:26977343 | A/G | 2.07E-5 | 145 | 12 | 7.73 | 1.2 | KM Plot |
| GBM | rs5760114 | chr22:24261747 | T/A | 0.000117 | 144 | 3.7 | 9.3 | 12.73 | KM Plot |
| GBM | rs5760116 | chr22:24263502 | C/G | 1.3E-6 | 143 | 2.4 | 10.77 | 12 | KM Plot |
| GBM | rs61324630 | chr17:27043559 | T/A | 1.76E-5 | 148 | 12 | 8.37 | 1.2 | KM Plot |
| GBM | rs61683151 | chr17:27021202 | C/T | 2.22E-5 | 146 | 12 | 8.37 | 1.2 | KM Plot |
| GBM | rs62544439 | chr9:26911237 | A/G | 5.8E-8 | 146 | 11.4 | 12.87 | 1.23 | KM Plot |
| GBM | rs6442465 | chr3:14715977 | G/C | 7.16E-5 | 149 | 1.1 | 12.8 | 10.77 | KM Plot |
| GBM | rs6442466 | chr3:14720135 | T/C | 7.11E-5 | 149 | 1.1 | 12.97 | 10.67 | KM Plot |
| GBM | rs6442467 | chr3:14720477 | G/A | 7.16E-5 | 149 | 1.1 | 12.8 | 10.77 | KM Plot |
| GBM | rs6442468 | chr3:14723750 | C/A | 7.76E-5 | 148 | 1.1 | 13.13 | 10.87 | KM Plot |
| GBM | rs6442469 | chr3:14726340 | T/C | 7.77E-5 | 147 | 1.1 | 12.97 | 10.67 | KM Plot |
| GBM | rs6485712 | chr11:12433635 | C/T | 8.04E-6 | 149 | 1.92 | 10.17 | 11.43 | KM Plot |
| GBM | rs66583794 | chr17:27008081 | A/G | 2.22E-5 | 146 | 12 | 8.37 | 1.2 | KM Plot |
| GBM | rs68127285 | chr22:24258983 | AAAGGG/A | 4.47E-7 | 145 | 2.4 | 9.93 | 12 | KM Plot |